It depends on the manager. With the way project work happens, you change managers with every project. I have had some transphobic managers, but not overtly transphobic. The policies protect you from them saying overtly transphobic things, but some definitely have treated me differently than all the cisgender people on the project and have done things like shared the fact that I was transgender with the entire project team before I even had my first day on the project. Thankfully, they do have an HR lead who is quite high up with real power who is dedicated to LGBTQ issues. So when I've found myself on projects such as these with those types of managers, I can email or call her, and I'll hear back normally within 24 hours. She then will help me navigate the situation by giving me several options on how to handle it, letting me make the ultimate choice on what I feel is best to do, and then supporting me in that action (even if it is getting of the project and onto a different one). When this has occurred, she has made sure I get moved to a good new project with a great manager. So bad initial experience in a few cases, but great effort to fix it and ensure that my career isn't hurt by it.